Leading Patient Engagement Software

Patient Engagement Software for Every Step of the Care Journey

Twistle puts the patient at the heart of the healthcare journey with patient engagement software proven to increase engagement and adherence, reduce complications, and drive return on investment through:

  • Customizable, automated messaging pathways
  • Rich library of proven multi-disciplinary clinical content
  • Seamless integration with existing EHR and CRM technology

Learn more by scheduling your personalized demo of Twistle.

A Trusted Partner of Leading Healthcare Organizations


Improving Patient Activation

Realize 90%+ Patient Engagement Rates

Twistle’s patient engagement software powers automated communication pathways that achieve consistently high engagement rates by delivering customizable support and monitoring to the patients who need it most. 

Flexible patient communication modalities enable engagement across:

  • SMS text
  • Your existing portal or digital front door
  • Twistle app
  • Interactive voice response (IVR)

Twistle makes it easy for your team to seamlessly deliver exceptional care.

Digital Patient Engagement Platform

Proven Clinical Content, Data-Driven Communication

Twistle’s automated, personalized care pathways empower patients through population health initiatives, and acute and chronic conditions to manage their health more effectively and independently.

Our clinical content and communication protocols automate and optimize patient engagement, improve outcomes and generate return on investment across a range of service lines including:

  • Chronic Care Management
  • Gastrointestinal
  • Cardiovascular
  • Orthopedics and Rheumatology
  • Women’s Health
  • And many more


“The ability to safely manage surgical patients post-discharge reduces costs, increases patient satisfaction, and has been particularly valuable amidst COVID-19.”

Board Certified Orthopedic Surgeon

Seamless EHR and CRM Integration

Streamlined Experience for Patients and Your Team

We built Twistle to seamlessly integrate with your EHR, CRM, and other systems so your team spends time where they’re needed most — with their patients.

Our patient engagement software integration enables automated patient outreach that is triggered through order sets, procedure schedules, population health milestones. Patients are
automatically enrolled and their response data is integrated back into source systems for a seamless clinical record.

Schedule a Personalized Demo of Twistle

Improving the Patient Experience

Ready to Get Started?

Want to deliver a care experience for patients that is proactively managed, personalized to their individual needs, and delivered in a way that keeps them activated throughout their care journey? Schedule a demo with one of our Twistle experts to see our patient engagement software in action and let’s get started.